Deseret News
Sunday, April 24, 1994


ARMY DEFENDS "INFORMED CONSENT" OF VOLUNTEERS

Worker says precautions "taken to extremes," but critics aren't impressed.
_________________________________________________________________

By Matthew S. Brown, Staff Writer

 

Forty years ago, Dave Ankarlo and other volunteers could have stood in a cloud of deadly nerve agent to test the effectiveness of the Army's chemical protective clothing.

And they may not have been told the risks involved.

But the Army says the rough and reckless days of germ warfare testing ended long ago. In a protective-clothing test conducted last year, Ankarlo was subjected to chemicals that only simulate the characteristics of actual nerve agents. He attended briefings about the hazards of the test and signed detailed consent forms. And he could have bailed out of the test at any time.

"All precautions were taken to extremes," he said in an interview. "If there were any concerns, there is no way in heck I would be involved in something like that."

Despite the precautions, the safety of test volunteers and workers at this isolated desert outpost is still questioned. Critics of military testing say issues surrounding Dugway's research work are the same
being debated nationally over past government plutonium experiments of unsuspecting citizens.

"The informed consent today doesn't always appear to be truly informed," said Steve Erickson, spokesman for the military watchdog group Downwinders. "And because of past problems we've seen at Dugway with the conduct of these experiments, we know things can go wrong, people get exposed and they have little recourse for justice after the fact.

"It's a credibility question," he added. "Can this command conduct useful research without stepping over the line resulting in real hazards to employees?"

Dugway testing will be among the topics discussed Wednesday in Washington, D.C., when the Senate Committee on Veterans Affairs holds hearings on what some lawmakers see as "a pattern" over the past 50 years of the military exposing people to dangerous concentrations of  hazardous material without fully explaining the risks, then leaving those people on their own to prove they had been harmed.

"We like to think that abuses such as radiation exposure, exposure to chemical or biological weapons and other outrages are a thing of the past, but the legacy continues," said committee chairman Sen. John D. Rockefeller, D-W.V.

But Dugway officials point to the recent Battledress Overgarment test as an example of current efforts to protect test volunteers and employees.

The clothing test also explains why the Army still conducts human experimentation.

"Dugway uses mannequins," said base spokeswoman Melynda Petrie. "But mannequins can't put protective clothing through its paces in a normal range of motions as humans could."

The test, conducted in November, was to determine the effectiveness of protective clothing issued to troops in the Persian Gulf War. The clothing - a jacket and pants made with material that absorbs chemical agents - had never been field tested against the aerosolized or "dusty" chemical agents believed to be possessed by Iraq.

"It was a concern to me, being in Desert Storm where we had to wear this stuff all the time," said Ankarlo, a 32-year-old mechanic and National Guardsman. "So I was glad doing a test like this . . . you could be protecting thousands of lives."

It was more than a sense of patriotic duty, however, that got Ankarlo to volunteer. It is his job, performed without additional pay, in addition to his primary duties as a mechanical technician.

His employer, Lockheed Corp., a private contractor at Dugway that conducted the test, asked about a dozen other employees with similar job descriptions to participate. None of them turned down the request, test officials said. Under Army policy, their identity is confidential unless they choose otherwise. Only Ankarlo and another volunteer consented to an interview with the Deseret News.

During the four-day test, they stood in a dry riverbed dressed in jacket, pants, overboots, gloves and hooded respirator while test officers sprayed a yellowish dust cloud of chemicals simulating actual aerosolized agents. After being sprayed, they ran in place or in a figure eight to determine if body movements allowed any simulant to leak through.

After the spraying and exercising, the volunteers filed into a trailer where they took off the clothing. Researchers then wetted a small area of skin and removed the water sample, which would be analyzed to find out if any simulant penetrated the clothing. Test results have not been released.

"Pretty neat," Ankarlo said, describing the test experience. "Sometimes you couldn't even see the guy right next to you. You were breathing, trying to smell it (through the hooded respirator), but you couldn't smell it."

"It was like being in a jet plane flying through a cloud," added volunteer Kerry Preston, an electrical technician.

Dugway sought input from the Human Use Committee at Army Test and Evaluation Command in Aberdeen, Md., before going forward with the test. But Dugway spokeswoman Petrie said submitting the test to the committee had nothing to do with the chemical simulants. It was because the test initially involved a new monitoring device - a pill containing a tiny microprocessor the volunteers would have ingested, allowing medical personnel to better monitor physical vital signs and heat exhaustion during the test.

But the pill didn't catch the committee's attention. "Because we were walking people through a cloud and we weren't familiar with the cloud, we wanted to send it to the surgeon general," said Pete DeLaney, human factors engineering group leader for the Army's Test and Evaluation Command.

The Army's surgeon general found the test a minimal risk to participants.

"Broadly speaking that means it's about as risky as most things in daily life," said Chuck Dasey, spokesman for the Army's Medical Research Development, Acquisition and Logistics command.

The cloud consisted of chemicals with health effects ranging from relatively harmless to toxic to unknown, depending on dosages and other variables (see chart). Volunteers wore the recommended respirator masks to protect them from possible hazards of inhaling the chemicals. An emergency medical staff was also on hand, and volunteers were required to shower three separate times after each day of testing.

But test officials indicated the chemical cloud didn't warrant all the precautions. "It's harmless stuff, but we have to cover our bases," Lockheed test officer Lamont Law said, noting that if the chemical cloud could have harmed anyone, he wouldn't have subjected his employees to it.

"They are my people. They are my assets. If they are gone, I am out of business," Law said. "If one of my guys went down because of heat overload, I would have run in the cloud without any protection."

But critics of military testing are suspect of the fearlessness of Dugway workers and assurances that simulants are harmless. They cite instances documented in past Deseret News reports of the Army using dangerous simulants and then stopping the practice after scientific literature revealed the substances caused debilitating and sometimes deadly diseases.

One case involved an infectious bacterium called serratia mercescens. The Army sprayed the exotic-sounding toxin over the San Francisco Bay area in 1950, sending 10 unsuspecting people to the hospital, one of whom died, with infections. The Army stopped using the simulant in 1979 after experts found the organism could cause meningitis, wound infection and arthritis.

In 1957, a Dugway-based experiment dropped zinc cadmium sulfide particles over a vast region of the eastern United States to detect dispersion of biological agents over a large land area. Then in 1973, scientific literature said the fluorescent particles used in such quantities were known to be toxic in almost all physiological systems. The simulant is no longer used.

More recently, the Army pulled a seemingly "safe" chemical - dimethyl methylphosphonate or DMMP - from its list of outdoor nerve agent simulants in 1988, when independent studies confirmed it was a  suspected carcinogen

Rutgers University professor Leonard A. Cole, who is working on a sequel to his 1988 book on military testing, "Clouds of Secrecy," said he found government researchers assume what may be harmless in one circumstance will remain harmless in others. "They introduce these (simulants) into the environment in odd ways, such as dense clouds, that increase the chance for infection."

Even the exemplary Battledress Overgarment test had its safety problems. In written comments submitted to the Army, Down-wind-ers criticized the lack of critical information in the consent form volunteers signed. The four-page document detailed the physical rigors of exercising in protective clothing and the risk of overexertion or heat exposure. But there was no mention of exposure to chemical simulants.

"They were given a very thorough briefing (on the simulants) before the test," assured Law. But, he acknowledged that not having the volunteers sign off on the simulants was a mistake that was corrected "after the fact" with another consent form detailing the simulants they had been exposed to.

Cole also criticized the test for lacking any follow-up examinations of volunteers or long-term monitoring. "One cannot be sure of the health consequences," he said.

Law said the volunteers were told to contact Dugway Health Clinic if they experienced any problems from the test.

But Ankarlo dismissed the consent-form mixup as "shuffling some paperwork" and said concerns over simulant testing are exaggerated.

"Every test I have been in has been nothing. All precautions are taken. Sometimes it seems like too many precautions," he said, noting he often helps set up testing equipment. "There are more risks with the chemicals at home."

But even Ankarlo has his limits on volunteering to be the guinea pig.

If I was on vacation or going fishing the next day, I wouldn't
volunteer," he said.

*****

ADDITIONAL INFORMATION

Components of a "dusty" cloud

Chemicals used to simulate a "dusty agent" cloud sprayed at human volunteers in the November 1993 Battledress Overgarment test:
 

- Syloid 244 - Tiny silica particles simulating grains of sand or dust. It is used in salts and seasonings. Safety literature cautions against skin contact or prolonged breathing of the dust. The drying action of silica can irritate skin and mucous membranes of the nose and throat. Chronic or long-term exposure could cause silicosis, and certain doses fed to rats showed it could causes lung tumors and lead to lymph node fibrosis.

- Uranine - Yellow or orange fluorescent crystals or powder used to dye wool and silk and in marking water for air and sea rescues. No data are available on the health effects of breathing Uranine, and it was minimally toxic when taken orally.

- Tinopal - A brightener used in detergents and soaps. Overexposure can be corrosive to the lungs, skin and eyes. Tinopal and Uranine allowed researchers to see and gauge whether any simulant penetrated the protective clothing to underclothing or skin.

- Tetraethylene glycol - Was used to dissolve the Uranine and Tinopal together. Can be harmful when inhaled, swallowed or absorbed by skin, causing irritation, nausea, headache and vomiting. Ethylene oxide, an experimental carcinogen, is used in producing the chemical and may be present as a contaminant.

Sources: Environmental assessment for the Battledress Overgarment Penetration Study and material safety data sheets issued by the chemicals' manufacturers.

 

 

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